Neonatal Drug Therapy Manual

Y-Site Injection Compatibility Chart

Y-SITE INJECTION COMPATIBILITY CHART*

 

A

m

p

i

c

i

l

l

i

n

C

a

 

g

l

u

c

o

n

a

t

e

C

l

o

x

a

c

i

l

l

i

n

 

D

o

b

u

t

a

m

i

n

e

 

 

D

o

p

a

m

i

n

e

E

p

i

n

e

p

h

r

i

n

e

F

e

n

t

a

n

y

l

F

u

r

o

s

e

m

i

d

e

 

G

e

n

t

a

m

i

c

i

n

H

e

p

a

r

i

n

 

0.5

u/mL

I

n

d

o

m

e

t

h

a

c

i

n

 

M

i

d

a

z

o

l

a

m

 

 

M

o

r

p

h

i

n

e

P

o

t

a

s

s

i

u

m

 

C

l

N

a

 

b

i

c

a

r

b

T

P

N

V

a

n

c

o

m

y

c

i

n

Ampicillin   c     x x     x c   x c c   x x
Ca gluconate c     ? c c c c c c x c c c x c c
Cloxacillin                 x c       c      
Dobutamine   ?     c c c x   ? x x c c x c c
Dopamine x c   c   c c x c c x c c c x c c
Epinephrine x c   c c   c c c c   c c c x   c
Fentanyl   c   c c c   c c c   c c c c c c
Furosemide   c   x x c c   x c ? x x c c c x
Gentamicin x c x   c c c x   c x c c c   c  
Heparin 0.5 u/mL c c c ? c c c c c     c c c c c c
Indomethacin   x   x x     ? x         c c x x
Midazolam x c   x c c c x c c     c c x x c
Morphine c c   c c c c x c c   c   c c c c
Potassium Cl c c c c c c c c c c c c c   c c c
Na bicarbonate   x   x x x c c   c c x c c   x x
TPN x c   x c   c c c c x x c c x   c
Vancomycin x c   c c c c x   c x c c c x c  

*= Information provided refers to most common drug concentrations used in neonates.

C= Compatible   X= Not compatible

?=Compatibility varies with concentration and specific conditions, please contact pharmacy

Blank= No information available

References:

-Trissel LA. Handbook on injectable drugs. 12th edition. American Society of Hospital Pharmacists. 2003. Texas

-King Guide to Parenteral Admixtures. King Guide to Parenteral Admixtures Internet Edition (online) 2006. Available from King Guide Publications, Inc. Accessed 21/11/2006.

Updated Nov 2006

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