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Anticholinergic- Anti-Parkinson's Agent
- Symptomatic relief of drug induced extrapyramidal side effects and acute dystonic reactions
Reconstitution and Stability:
- Available as a 1 mg/mL injection
- Stable at room temperature, protect from light
- Solutions Compatible: no information
- Additives/Above Cassette Compatible: perphenazine
- Y-site Compatible: fluconazole
- Incompatible: no information
(For approved routes of administration by nursing personnel, refer to Policy for the Administration of Intravenous Medications.)
YES, rarely used- onset of effect is similar to IM
|IV Intermittent Infusion
|IV Continuous Infusion
(For neonatal dosages, refer to Neonatal IV Drug Manual.)
Drug Induced Extrapyramidal Disorders:
- Pediatrics(> 3 years): 0.02 - 0.05 mg/kg/dose 1-2 times daily
- Use in children <3 years should be reserved for life-threatening emergencies
- Adults: 1-4 mg/dose 1-2 times daily
Acute Dystonic Reactions:
- Adults: 2 mg IM or IV then 1 - 2 mg BID for 2 - 3 days
Potential hazards of parenteral administration:
- Mental confusion, excitement
- CNS drowsiness, nervousness
- Weakness, nausea
- This medication is highly anticholinergic and when used in combination with major tranquilizers will produce additive anticholinergic effects:
- dry mouth
- blurred vision
- urinary retention
- Rarely produces anticholinergic psychosis
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