- To provide rapid relief of anaphylaxis and hypersensitivity reactions.
- To restore cardiac rhythm in cardiac arrest.
- To provide circulatory support.
- Stable at room temperature. Protect from light and air
- Solution should not be used if brown in colour or contains precipitate
- Solutions Compatible: dextrose up to D10W, 0.9% NaCl, dextrose-saline combinations, ringer's solution, ringer's lactate
- Additives/Above Cassette Compatible: no information
- Y-site Compatible: amino acids/dextrose, dobutamine, dopamine, morphine, pancuronium, KCl (up to 40 mmol/L), SMOF lipid 20%, - Incompatible: alkaline solutions (sodium bicarbonate),
(For approved routes of administration by nursing personnel, refer to Policy for the Administration of Intravenous Medications.)
YES. FOR ANAPHYLAXIS
Note: 1 mg/mL = 1:1000
YES. FOR PALS
NOT for anaphylaxis
Note: 0.1 mg/mL = 1:10,000
|IV Continuous Infusion||
Click here to access SDC Drug Infusion Sheet
(For neonatal dosages, refer to Neonatal IV Drug Manual.)
- 0.01 mg/kg/dose IM = 0.01 mL/kg/dose of 1 mg/mL (1:1000) Q 5 minutes PRN x 3 doses (Max: 0.5 mg/dose)
- IM Epi-Pen:
<30 kg: 0.15 mg
>30 kg: 0.30 mg
- Patient can use their own supply of Epi-Pen while admitted - keep the supply at patient's bedside
- - RESUSCITATION (PALS):
- 0.01 mg/kg/dose = 0.1 mL/kg/dose of 0.1 mg/mL (1:10,000) IV/IO Q 3-5 minutes PRN
- CONTINUOUS IV INFUSION
- 0.01-1 microgram/kg/minute
- Most common (transient): fever, anxiety, tenseness, restlessness, throbbing headache, tremor, weakness, dizziness, pallor, respiratory difficulty
- Peripheral constriction leading to pulmonary edema
- Repeated local injections can result in necrosis at sites of injection from vascular constriction
- Ventricular fibrillation
- If extravasation occurs, click HERE for treatment guidelines.
- Monitor EKG, HR, BP, site of infusion for extravasation/excessive blanching
- Use with caution in patients with cardiovascular disease, hypertension, diabetes, hyperthyroidism
- Contraindicated in narrow angle glaucoma, shock, general anaesthesia with halogenated hydrocarbons, organic brain syndrome, labor, patients receiving MAO inhibitors
1 mg/mL = 1:1000
0.1 mg/mL = 1:10,000
DILUTED EPINEPHRINE 10 mcg/mL
FOR MINI BOLUS DOSING
- Diluted epinephrine may be requested by physicians during resus cases.
- It is sometimes referred to as an "Epi Spritzer".
- It is a fast way to give small bolus doses (usually 1/10 – 1/20 of the usual PALS IV/IO dose).
- The physician will use the 10 ml diluted epi syringe to administer small mini boluses (eg 0.5 mL, 1 mL).
A 10 mL syringe of Diluted Epinephrine is made by adding 1 mL of Epinephrine 0. 1 mg/mL to 9mL of NaCL 0.9%.
|Epinephrine 0.1 mg/mL (1:10,000)||1 mL|
|NaCL 0.9%||9 mL|