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- Treatment or prevention of zinc deficiency
- Intended for use as an additive to total parenteral nutrition solutions
Reconstitution and Stability:
- Available as a 5 mg/mL solution
- Stable at room temperature
- Stable for 24 hours when diluted in TPN
- Additive/buretrol Compatible: TPN (amino acids/dextrose)
(For approved routes of administration by nursing personnel, refer to Policy for the Administration of Intravenous Medications.)
|IV Intermittent Infusion
|IV Continuous Infusion
||YES, intended for use as an additive to TPN
(For neonatal dosages, refer to Neonatal IV Drug Manual.)
In terms of elemental zinc
- <3 months: 300 mcg/kg/day
- >3 months - <5 years: 100 mcg/kg/day (maximum: 5 mg/day)
- >5 years: 2.5-5 mg/day
Potential hazards of parenteral administration:
- Zinc overdose is possible, but unlikely if above dosing guidelines are followed
- Symptoms of zinc overdose: nausea, vomiting, dehydration, electrolyte imbalances, dizziness, abdominal pain
- Zinc sulfate contains 23% elemental zinc
- Monitor serum zinc (normal: 10-20 micromol/L)
- Gross excess of zinc can interfere with copper absorption and metabolism
- Do not give undiluted due to phlebitis, tissue irritation and potential increased renal loss of minerals from a bolus injection
- Signs and symptoms of zinc deficiency include:
Growth suppression, anorexia, abnormal taste perception, skin lesions, diarrhea, alopecia
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