- Treatment of iron deficiency in combination with erythropoeitin where oral iron preparations cannot provide adequate supplementation, particularly in dialysis patients
- 100 mg/5 mL ampoule (20 mg/mL)
- Store at room temperature. Protect from light
- Stable for 48 hours at room temperature or in the fridge when diluted in NS at a concentration of 0.5 - 2 mg/mL and stored in minibags or plastic syringes
- Solutions Compatible: NS
- Additives/Above Cassette Compatible: no information
- Y-site Compatible: no information
Incompatible: DO NOT mix with other drugs or add to parenteral nutrition solutions
(For approved routes of administration by nursing personnel, refer to Policy for the Administration of Intravenous Medications.)
YES , doses < 100 mg only
|IV Intermittent Infusion||
YES, doses < 100 mg only
|IV Continuous Infusion||NO|
(For neonatal dosages, refer to Neonatal IV Drug Manual.)
- 2 mg/kg once weekly
- Maximum: 7 mg/kg (up to 300 mg) for Non Renal patients. Doses of 7 mg/kg (up to 500 mg) in Non-Hemodialysis patients.
- 100 mg 1-3 times/week to a cumulative dose of 1000 mg
- Maximum IV push: 100 mg
- Maximum IV intermittent: 200 mg
- Anaphylaxis, urticaria
- Hypotensive reactions, especially with rapid injection
- Phlebitis, venous spasm
- Fever, edema, muscle pain, parathesia
- Wheeze, bronchospasm, chest pain, shivering, dyspnea, cyanosis, respiratory arrest
- Nausea, headache, vomiting
- Reduced absorption of oral iron (concurrent therapy not recommended)
- Iron sucrose is reported to have fewer adverse reactions and allergic reactions than iron dextran and may be used in patients who have reacted to iron dextran
- Patients receiving oral iron should hold it throughout the course of therapy with IV iron
- Serum Fe indices may not be accurate when drawn too close to IV iron administration. Try to allow at least one week after administration of IV iron before measuring.
- See "Intravenous Iron Therapy for Pediatric Hemodialysis Patients" in the dialysis unit
- Have epinephrine, diphenhydramine and hydrocortisone available at bedside and in portable kit for patient transport off unit.
- Dosage guidelines (Administer in sequence listed):
- Epinephrine (Adrenalin®) (1:1,000 is 1 mg/mL)______ mg = _______mL(0.01 mg/kg/dose = 0.01 mL/kg/dose, Max. 0.5 mg = 0.5 mL) IM in the thigh or alternative large muscle q15 minutes x 2, then Q4H PRN.
- Diphenhydramine [Benadryl®] __________ mg (1 mg/kg/dose, Max. 50 mg) I.V. x 1, then Q6H PRN.
- Hydrocortisone [Solu-cortef®] __________ mg (2.5 mg/kg/dose) I.V. x 1, then Q4H PRN