Parenteral Manual

Salbutamol

Disclaimer: Official controlled document is the CHEO online copy. It is the responsibility of user to ensure that any paper copy version is the same as the online version before use.

Alternate Name(s): 
VENTOLIN®, ALBUTEROL
Classification: 
Bronchodilator; B2-Adrenergic agonist
Original Date: 
August 2005
Revised Date: 
June 2017
Indications: 
  • For the relief of severe bronchospasm in acute asthma                    
  • Treatment of status asthmaticus
Reconstitution and Stability: 
  • Available as a 1 mg/mL (1000 mcg/mL) solution - 5 mL ampoules               
  • Protect from light
  • Stable at room temperature
  • Diluted solutions stable 24 hours at room temperature
Compatibility: 

- Solutions Compatible: D5W, 0.9% NS, dextrose-saline combinations, Sterile Water for Injection

- Y-site Compatible: morphine

- NO INFORMATION on compatibility with KCl or TPN

Administration: 

(For approved routes of administration by nursing personnel, refer to Policy for the Administration of Intravenous Medications.)

SC NO
IM NO
IV Direct

NO

IV Intermittent Infusion NO
IV Continuous Infusion

YES,  NOT recommended except in PICU
Usual dilution: 0.5 mg/mL

Click  here to access SDC Drug Infusion Sheet

Dosage: 

(For neonatal dosages, refer to Neonatal IV Drug Manual.)

Pediatric:

  • 1 mcg/kg/minute; increase by 1 mcg/kg/minute Q 10-20 minutes PRN
  • Maximum: 10 mcg/kg/minute

Adolescent/adult:

  • continuous IV infusion:  5 mcg/minute initially, increase if required to 10 mcg/minute and 20 mcg/minute at 15 - 30 minutes interval. 
  • Maximum:  50 mcg/minute; doses as high as 80 mcg may be required
Potential hazards of parenteral administration: 
  • May cause tremor, nervousness, headache, nausea, dizziness, increased sweating, warmth, tachycardia, mild hypotension
  • Hypokalemia, hyperglycemia
Notes: 
  • Monitor heart rate, respiratory rate, serum potassium, serum glucose
  • Signs of overdose include: severe tachycardia, arrhythmias, hypertension

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