Papaverine hydrochloride (NON-FORMULARY)
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- Relief of cerebral and peripheral ischemia associated with arterial spasm
Reconstitution and Stability:
- Stable at room temperature; DO NOT refrigerate
- Protect from light
- Solution is clear and colourless to pale yellow
- Solutions Compatible: dextrose solutions up to D10W, 0.9% NaCl, dextrose-saline combinations, ringer's solution
- Additive/Above Cassette Compatible: no information
- Y-site Compatible: no information
Incompatible: ringer's lactate (precipitate forms), alkaline solutions, aminophylline
(For approved routes of administration by nursing personnel, refer to Policy for the Administration of Intravenous Medications.)
Usual dilution: undiluted or dilute in equal volume of SWI
Infusion time: 1-2 minutes
|IV Intermittant Infusion
|IV Continuous Infusion
(For neonatal dosages, refer to Neonatal IV Drug Manual.)
- 30-120 mg IM/IV, may repeat q3h PRN
Potential hazards of parenteral administration:
- Rapid IV administration may result in arrhythmias and apnea
- Thrombophlebitis at site of injection
- Flushing of face, tachycardia, hypotension
- Drowsiness, vertigo
- Caution in patients with glaucoma; monitor intraocular pressure
- Should not be used in neonates due to the increased risk of drug-induced cerebral vasodilation and possibility of an intracranial bleed.
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