Neonatal Drug Therapy Manual

Fluticasone Proprionate

Disclaimer: Official controlled document is the CHEO and Ottawa Hospital online copy. It is the responsibility of user to ensure that any paper copy version is the same as the online version before use.

Alternate Name(s): 
  • Adjunctive treatment for BPD
  • Metered-dose inhaler, use with aerochamber
  • 1 - 2 puffs (125 - 250 mcg) BID
Side Effects: 
  • GI: dry mouth, oral candidiasis
  • Respiratory: bronchospasm, cough, hoarseness

As fluticasone has an extremely low oral bioavailability (<1%), systemic effects are minimal

Reconstitution and Stability: 




  • If salbutamol or ipratropium is also ordered, give salbutamol or ipratropium first, wait 5 minutes and then administer fluticasone
  • After each administration, rinse mouth

-Taketomo CK, Hodding JH, Kraus DM. Pediatric Dosage Handbook 9th-11th Editions. Hudson: Lexi-Comp Inc.; 2002-2004.

 -Young TE, Mangum B. Neofax(R).13th-16th Editions. Raleigh: Acorn Publishing; 2000-2003.

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