Neonatal Drug Therapy Manual

Pneumococcal Conjugate Vaccine

Disclaimer: Official controlled document is the CHEO and Ottawa Hospital online copy. It is the responsibility of user to ensure that any paper copy version is the same as the online version before use.

Alternate Name(s): 
Prevnar 13
Original Date: 
March 2005
Revised Date: 
September 2018
  • Routine childhood immunization
  • IM
  • Can be co-administered with the following vaccines (at separate injection sites): Hepatitis B, Pediacel
  • 0.5 mL IM at 2, 4, and 12 months of age for a total of 3 doses
Side Effects: 
  • Local: transient redness at the injection site
  • Systemic: fever (more frequently reported when co-administered with other vaccines), drowsiness, irritability
Parameters to Monitor: 
  • Injection site
  • Temperature
Reconstitution and Stability: 




  • Refrigerate until ready to use
  • Prevnar 13 is a pneumococcal conjugated vaccine that contains antigen from 13 pneumococcal serotypes: 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F

- Publicly Funded Immunization Schedule for Ontario.  Ontario MOH Immunization Schedules December 2016

- Chen J, Lau E (editors). Drug Handbook and Formulary. The Hospital for Sick Children.Toronto: Department of Pharmacy; 2017-2018


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