Neonatal Drug Therapy Manual


Disclaimer: Official controlled document is the CHEO and Ottawa Hospital online copy. It is the responsibility of user to ensure that any paper copy version is the same as the online version before use.

Alternate Name(s): 
Original Date: 
January 2018
Revised Date: 
November 2018
  • Treatment of Influenza A and B infection
  • PO

Preterm (< 36 weeks GA):

  • 1 mg/kg/dose twice daily for 5 days


Term (> 37 weeks GA)

  • 3 mg/kg/dose twice daily for 5 days

Dosage adjustment may be required in renal impairment.  Refer to available references or clinical pharmacist for dosage adjustment.

Side Effects: 
  • GI: diarrhea, nausea, vomiting
Reconstitution and Stability: 




  • AAP COMMITTEE ON INFECTIOUS DISEASES. Recommendations for Prevention and Control of Influenza in Children, 2018–2019. Pediatrics. 2018;142(4):e20182367

  • McPherson C, Warner B, Hunstad D.A, et al.  Oseltamivir Dosing in Premature Infants.  journal of Infectious Diseases 2012; 206: 847-850.

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