||Neonatal Drug Therapy Manual
Disclaimer: Official controlled document is the CHEO and Ottawa Hospital online copy. It is the responsibility of user to ensure that any paper copy version is the same as the online version before use.
Blood Product Derivatives; Plasma Protein
||Albumin 5% (0.05 g/mL)
||Albumin 25% (0.25 g/mL)
||Intravascular volume expansion
Protein-losing states (chylothorax, nephrotic syndrome)
0.5 - 1 g/kg/dose
(10 - 20 mL/kg/dose)
0.5 - 1 g/kg/dose
(2 - 4 mL/kg/dose)
over 30 - 60 minutes
over 2 hours
- CVS: rapid infusion may cause vascular overload and precipitate heart failure
- Hypersensitivity reactions may include chills, fever, nausea, urticaria
Reconstitution and Stability:
- Solutions Compatible: Dextrose (up to D10W), 0.9% NaCl
- Y-site Compatible: amino acids and dextrose
- Incompatible: Sterile water for injection, lipids, midazolam, vancomycin
- Use within 4 hours after opening
- Do not use if solution shows sediment
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