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Neonatal Drug Therapy Manual |
Diltiazem
Disclaimer: Official controlled document is the CHEO and Ottawa Hospital online copy. It is the responsibility of user to ensure that any paper copy version is the same as the online version before use.
Indications:
- Myocardinal hypertrophy
- Pulmonary hypertension
Administration:
-
IV continuous infusion
-
PO
Dosage:
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IV:
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5 - 30 mcg/kg/min (pulmonary hypertension)
-
PO:
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1 mg/kg/day divided BID, increase as needed to 4 mg/kg/day divided BID or QID
Side Effects:
-
CVS: hypotension, arrhythmia, flushing
-
Local: burning at IV site
Reconstitution and Stability:
Compatibility:
- Solutions Compatible: D5W, 0.9% NaCl, dextrose-saline combinations
- Y-site Compatible: dopamine, dobutamine
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